Boosting immune function is one of the biggest topics in our clinic right now, so we though we would aggregate a selection of current research publications pertaining to micronutrients and their biological roles in immune function. Articles are linked to their original source. Search articles published in the Journal of Orthomolecular Medicine Search articles published by the Orthomolecular Medicine News Service |
Vitamin C
- Patients with community acquired pneumonia exhibit depleted vitamin C status and elevated oxidative stress. Nutrients. 2020; https://doi.org/10.3390/nu12051318
- Quercetin and vitamin C: An experimental, synergistic therapy for the prevention and treatment of SARS-Cov-2. Frontiers in Immunology. 2020; https://doi.org/10.3389/fimmu.2020.01451
- Intravenous vitamin C for reduction of cytokines storm in acute respiratory distress syndrome. PharmaNutrition. 2020; https://doi.org/10.1016/j.phanu.2020.100190
- Can early and high intravenous dose of vitamin C prevent and treat coronavirus disease 2019 (COVID-19)? Medicine in Drug Discovery. 2020; https://doi.org/10.1016/j.medidd.2020.100028
- Vitamin C may reduce the duration of mechanical ventilation in critically ill patients: A meta-regression analysis. Journal of Intensive Care. 2020; https://doi.org/10.1186/s40560-020-0432-y
- Vitamin C can shorten the length of stay in the ICU: A meta-analysis. Nutrients. 2019;
Vitamin D
- Perspective: Improving vitamin D status in the management of COVID-19. Eur J Clin Nutr. 2020; https://doi.org/10.1038/s41430-020-0661-0
- Vitamin D and COVID-19: Do deficient risk a poorer outcome? Lancet Diabetes Endocrinol. 2020; https://doi.org/10.1016/S2213-8587(20)30183-2
- Vitamin D deficiency and the COVID-19 pandemic. J Glob Antimicrob Resist. 2020; https://doi.org/10.1016/j.jgar.2020.05.006
- The role of Vitamin D in the prevention of coronavirus disease 2019 infection and mortality. Aging Clin Exp Res. 2020; https://doi.org/10.1007/s40520-020-01570-8
- 25-Hydroxyvitamin D concentrations are lower in patients with positive PCR for SARS-CoV-2. Nutrients. 2020; https://doi.org/10.3390/nu12051359
- Evidence supports a causal model for vitamin D in COVID-19 outcomes (Epub ahead of print) MedRxiv. 2020; https://doi.org/10.1101/2020.05.01.20087965
- Vitamin D insufficiency is prevalent in severe COVID-19 (Epub ahead of print) MedRxiv. 2020; https://doi.org/10.1101/2020.04.24.20075838
- Does vitamin D status impact mortality from SARS-CoV-2 infection? Medicine in Drug Discovery. 2020; https://doi.org/10.1016/j.medidd.2020.100041
- The role of vitamin D in the prevention of coronavirus disease 2019 infection and mortality. Infectious Diseases. 2020; https://doi.org/10.21203/rs.3.rs-21211/v1
- Evidence that vitamin D supplementation could reduce risk of influenza and COVID-19 infections and deaths. Nutrients. 2020; https://doi.org/10.3390/nu12040988
Selenium
- Selenium supplementation in the prevention of coronavirus infections (COVID-19). Med Hypotheses. 2020; https://doi.org/10.1016/j.mehy.2020.109878
- Association between regional selenium status and reported outcome of COVID-19 cases in China. Am J Clin Nutr. 2020; https://doi.org/10.1093/ajcn/nqaa095
Zinc
- COVID-19 pandemic: Can maintaining optimal zinc balance enhance host resistance? Tohoku J Exp Med. 2020; https://doi.org/10.1620/tjem.251.175
- Can Zn be a critical element in COVID-19 treatment? [Epub ahead of print] Biol Trace Elem Res. 2020; https://doi.org/10.1007/s12011-020-02194-9
- Hydroxychloroquine and azithromycin plus zinc vs hydroxychloroquine and azithromycin alone: Outcomes in hospitalized COVID-19 patients. [Epub ahead of print] MedRxiv. 2020; https://doi.org/10.1101/2020.05.02.20080036
- Improving the efficacy of chloroquine and hydroxychloroquine against SARS-CoV-2 may require zinc additives: A better synergy for future COVID-19 clinical trials. Le Infezioni in Medicina. 2020; https://www.infezmed.it/media/journal/Vol_28_2_2020_9.pdf
Micronutrients and Nutrition
- Diet supplementation, probiotics, and nutraceuticals in SARS-CoV-2 infection: A scoping review. Nutrients. 2020; https://doi.org/10.3390/nu12061718
- Strengthening the immune system and reducing inflammation and oxidative stress through diet and nutrition: Considerations during the COVID-19 crisis. Nutrients. 2020; https://doi.org/10.3390/nu12061562
- The impact of nutrition on COVID-19 susceptibility and long-term consequences. Brain Behav Immun. 2020; https://doi.org/10.1016/j.bbi.2020.04.040
- Nutrition, immunity and COVID-19. BMJ Nutrition, Prevention & Health. 2020; http://dx.doi.org/10.1136/bmjnph-2020-000085
- What is the role of supplementation with ascorbic acid, zinc, vitamin D, or N-acetylcysteine for prevention or treatment of COVID-19? Cleve Clin J Med. 2020; https://doi.org/10.3949/ccjm.87a.ccc046
- Strengthening the immune system and reducing inflammation and oxidative stress through diet and nutrition: Considerations during the COVID-19 crisis. Nutrients. 2020; https://doi.org/10.3390/nu12061562
- COVID-19: The inflammation link and the role of nutrition in potential mitigation. Nutrients. 2020; https://doi.org/10.3390/nu12051466
- Impact of nutrition and diet on COVID-19 infection and implications for kidney health and kidney disease management. Journal of Renal Nutrition. 2020; https://dx.doi.org/10.1053%2Fj.jrn.2020.03.006
- Optimal nutritional status for a well-functioning immune system is an important factor to protect against viral infections. Nutrients. 2020; https://doi.org/10.3390/nu12041181
- Enhancing immunity in viral infections, with special emphasis on COVID-19: A review. Diabetes & Metabolic Syndrome. 2020; https://doi.org/10.1016/j.dsx.2020.04.015
- Potential interventions for novel coronavirus in China: A systematic review. Journal of Medical Virology. 2020; https://doi.org/10.1002/jmv.25707
- Early nutritional supplementation in non-critically ill patients hospitalized for the 2019 novel coronavirus disease (COVID-19): Rationale and feasibility of a shared pragmatic protocol. Nutrition. 2020; https://doi.org/10.1016/j.nut.2020.110835
- Nutrition support in the time of SARS-CoV-2 (COVID-19). Nutrition. 2020; https://doi.org/10.1016/j.nut.2020.110834
- Medical nutrition therapy for critically ill patients with COVID-19. European Review for Medical and Pharmacological Sciences. 2020; https://doi.org/10.26355/eurrev_202004_20874
- Optimal nutritional status for a well-functioning immune system is an important factor to protect against viral infections. Nutrients. 2020; https://doi.org/10.3390/nu12041181
- Nutritional modulation of immune function: Analysis of evidence, mechanisms, and clinical relevance. Frontiers in Immunology. 2019; https://doi.org/10.3389/fimmu.2018.03160
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