Boosting Immune Function

Vitamin C

• Patients with community acquired pneumonia exhibit depleted vitamin C status and elevated oxidative stress. Nutrients. 2020; https://doi.org/10.3390/nu12051318
• Quercetin and vitamin C: An experimental, synergistic therapy for the prevention and treatment of SARS-Cov-2. Frontiers in Immunology. 2020; https://doi.org/10.3389/fimmu.2020.01451
• Intravenous vitamin C for reduction of cytokines storm in acute respiratory distress syndrome. PharmaNutrition. 2020; https://doi.org/10.1016/j.phanu.2020.100190
• Can early and high intravenous dose of vitamin C prevent and treat coronavirus disease 2019 (COVID-19)? Medicine in Drug Discovery. 2020; https://doi.org/10.1016/j.medidd.2020.100028
• Vitamin C may reduce the duration of mechanical ventilation in critically ill patients: A meta-regression analysis. Journal of Intensive Care. 2020; https://doi.org/10.1186/s40560-020-0432-y
• Vitamin C can shorten the length of stay in the ICU: A meta-analysis. Nutrients. 2019;

Vitamin D

• Perspective: Improving vitamin D status in the management of COVID-19. Eur J Clin Nutr. 2020; https://doi.org/10.1038/s41430-020-0661-0
• Vitamin D and COVID-19: Do deficient risk a poorer outcome? Lancet Diabetes Endocrinol. 2020; https://doi.org/10.1016/S2213-8587(20)30183-2
• Vitamin D deficiency and the COVID-19 pandemic. J Glob Antimicrob Resist. 2020; https://doi.org/10.1016/j.jgar.2020.05.006
• The role of Vitamin D in the prevention of coronavirus disease 2019 infection and mortality. Aging Clin Exp Res. 2020; https://doi.org/10.1007/s40520-020-01570-8
• 25-Hydroxyvitamin D concentrations are lower in patients with positive PCR for SARS-CoV-2. Nutrients. 2020; https://doi.org/10.3390/nu12051359
• Evidence supports a causal model for vitamin D in COVID-19 outcomes (Epub ahead of print) MedRxiv. 2020; https://doi.org/10.1101/2020.05.01.20087965
• Vitamin D insufficiency is prevalent in severe COVID-19 (Epub ahead of print) MedRxiv. 2020; https://doi.org/10.1101/2020.04.24.20075838
• Does vitamin D status impact mortality from SARS-CoV-2 infection? Medicine in Drug Discovery. 2020; https://doi.org/10.1016/j.medidd.2020.100041
• The role of vitamin D in the prevention of coronavirus disease 2019 infection and mortality. Infectious Diseases. 2020; https://doi.org/10.21203/rs.3.rs-21211/v1
• Evidence that vitamin D supplementation could reduce risk of influenza and COVID-19 infections and deaths. Nutrients. 2020; https://doi.org/10.3390/nu12040988

Selenium

• Selenium supplementation in the prevention of coronavirus infections (COVID-19). Med Hypotheses. 2020; https://doi.org/10.1016/j.mehy.2020.109878
• Association between regional selenium status and reported outcome of COVID-19 cases in China. Am J Clin Nutr. 2020; https://doi.org/10.1093/ajcn/nqaa095

Zinc

• COVID-19 pandemic: Can maintaining optimal zinc balance enhance host resistance? Tohoku J Exp Med. 2020; https://doi.org/10.1620/tjem.251.175
• Can Zn be a critical element in COVID-19 treatment? [Epub ahead of print] Biol Trace Elem Res. 2020; https://doi.org/10.1007/s12011-020-02194-9
• Hydroxychloroquine and azithromycin plus zinc vs hydroxychloroquine and azithromycin alone: Outcomes in hospitalized COVID-19 patients. [Epub ahead of print] MedRxiv. 2020; https://doi.org/10.1101/2020.05.02.20080036
• Improving the efficacy of chloroquine and hydroxychloroquine against SARS-CoV-2 may require zinc additives: A better synergy for future COVID-19 clinical trials. Le Infezioni in Medicina. 2020; https://www.infezmed.it/media/journal/Vol_28_2_2020_9.pdf

Micronutrients and Nutrition

• Diet supplementation, probiotics, and nutraceuticals in SARS-CoV-2 infection: A scoping review. Nutrients. 2020; https://doi.org/10.3390/nu12061718
• Strengthening the immune system and reducing inflammation and oxidative stress through diet and nutrition: Considerations during the COVID-19 crisis. Nutrients. 2020; https://doi.org/10.3390/nu12061562
• The impact of nutrition on COVID-19 susceptibility and long-term consequences. Brain Behav Immun. 2020; https://doi.org/10.1016/j.bbi.2020.04.040
• Nutrition, immunity and COVID-19. BMJ Nutrition, Prevention & Health. 2020; http://dx.doi.org/10.1136/bmjnph-2020-000085
• What is the role of supplementation with ascorbic acid, zinc, vitamin D, or N-acetylcysteine for prevention or treatment of COVID-19? Cleve Clin J Med. 2020; https://doi.org/10.3949/ccjm.87a.ccc046
• Strengthening the immune system and reducing inflammation and oxidative stress through diet and nutrition: Considerations during the COVID-19 crisis. Nutrients. 2020; https://doi.org/10.3390/nu12061562
• COVID-19: The inflammation link and the role of nutrition in potential mitigation. Nutrients. 2020; https://doi.org/10.3390/nu12051466
• Impact of nutrition and diet on COVID-19 infection and implications for kidney health and kidney disease management. Journal of Renal Nutrition. 2020; https://dx.doi.org/10.1053%2Fj.jrn.2020.03.006
• Optimal nutritional status for a well-functioning immune system is an important factor to protect against viral infections. Nutrients. 2020; https://doi.org/10.3390/nu12041181
• Enhancing immunity in viral infections, with special emphasis on COVID-19: A review. Diabetes & Metabolic Syndrome. 2020; https://doi.org/10.1016/j.dsx.2020.04.015
• Potential interventions for novel coronavirus in China: A systematic review. Journal of Medical Virology. 2020; https://doi.org/10.1002/jmv.25707
• Early nutritional supplementation in non-critically ill patients hospitalized for the 2019 novel coronavirus disease (COVID-19): Rationale and feasibility of a shared pragmatic protocol. Nutrition. 2020; https://doi.org/10.1016/j.nut.2020.110835
• Nutrition support in the time of SARS-CoV-2 (COVID-19). Nutrition. 2020; https://doi.org/10.1016/j.nut.2020.110834
• Medical nutrition therapy for critically ill patients with COVID-19. European Review for Medical and Pharmacological Sciences. 2020; https://doi.org/10.26355/eurrev_202004_20874
• Optimal nutritional status for a well-functioning immune system is an important factor to protect against viral infections. Nutrients. 2020; https://doi.org/10.3390/nu12041181
• Nutritional modulation of immune function: Analysis of evidence, mechanisms, and clinical relevance. Frontiers in Immunology. 2019; https://doi.org/10.3389/fimmu.2018.03160